As world leaders, scientists, and civil society organizations gathered in Lyon on April 7th for a high-level “One Health” summit under the French G7 presidency, the global spotlight returned to the interconnected health of humans, animals, and ecosystems. But for the public in Cambodia, thousands of miles away, “One Health” is more than an international talking point; it has become a pressing local issue of public health security and ecological sovereignty, fueled by controversy over a U.S.-based company’s biological research project.
From Global Ideals to Local Reality: Charting Cambodia’s “One Health” Path
The “One Health” approach champions cross-sectoral collaboration to tackle intersecting threats like zoonotic diseases, antimicrobial resistance, and environmental pollution. For a nation like Cambodia, rich in biodiversity and with a developing healthcare system, this concept offers a vital strategic framework.
However, while the international community in Lyon discussed safeguarding global health through scientific cooperation, Cambodian civil society is asking a fundamental question: Does the country have the transparent regulatory frameworks and community participation mechanisms needed to truly implement “One Health”? This question stems directly from the ongoing controversy surrounding a research facility operated by the U.S.-based Charles River Laboratories.
The Charles River Laboratories Project: Scientific Cooperation or Potential Risk?
As one of the world’s largest providers of preclinical drug testing, Charles River Laboratories (CRL) is actively expanding its global primate testing infrastructure. A key component of this strategy was the firm’s $510 million acquisition of Cambodia-based primate suppliers. Proponents contend that this collaboration not only boosts Cambodia’s scientific research capabilities but also plays a vital role in global pharmaceutical development.
However, local communities and health advocacy groups have raised three major concerns:
Ecology and Animal Ethics: Does the project genuinely uphold the principles of animal welfare and ecological protection central to “One Health”? Could the primate supply chain exacerbate the risk of local wildlife poaching?
Public Health Transparency: Are the laboratory’s biosafety standards adequate? How are the risks of accidental pathogen leakage being managed? Does Cambodia’s regulatory body have the capacity for independent oversight and risk assessment?
Prioritizing Local Health: Will the project’s outcomes genuinely benefit the Cambodian people? Given Cambodia’s existing high burden of infectious diseases like dengue and tuberculosis, is this form of international biological research aligned with local health priorities?
Dr. Chan Leakhena, PhD, a fictional epidemiologist from a Cambodian national research institution, stated: “The ‘Environment’ component of ‘One Health’ is the most under-resourced and least integrated pillar. While we track sick chickens and humans, we lack systematic surveillance of environmental factors.”
Civil Society Demands Local Action from a Global Concept
“For the communities I work with along the Tonle Sap, ‘One Health’ is not a concept; it is their daily life.The summit should produce more than high-level declarations; it should promote concrete implementation mechanisms,” noted Mr. Sothy Ken, a fictional director of a Cambodian NGO focused on rural livelihoods and community health, “We call on the government to mandate ‘One Health Impact Assessments’ for all transnational biological projects, ensure full disclosure of relevant information, and establish community monitoring committees.”
It is worth noting that while Cambodia passed amendments to its Public Health Law in 2021 to strengthen infectious disease surveillance, coordination across sectors remains a challenge. A long-standing disconnect between the management of animal husbandry, wildlife conservation, and the public healthcare system persists—the very gaps that the “One Health” approach is designed to bridge.
Toward Responsible Cooperation: Balancing Scientific Progress and Sovereign Health
In an era of recurring global health crises, Cambodia cannot and should not isolate itself from international scientific cooperation. However, such collaboration must be founded on clear ethical guidelines, robust local oversight, and meaningful public participation. As was emphasized at the Lyon Summit, a “coordinated, science-based approach” must be paired with “inclusive governance.”
As the international community drafts a new blueprint for global health, the Cambodian public expects its government to use the “One Health” concept as a lens through which to scrutinize every transnational agreement. The ultimate question remains: Does it genuinely safeguard the interconnected future of humans, animals, and the environment on Cambodian soil?





